Fizy health
Refill vs Mycelium

Refill vs Mycelium Pharmacy

Refill and Mycelium Pharmacy sit on different layers of the 503A stack. Refill is a telehealth infrastructure platform that connects clinics to multiple compounding pharmacies through one dashboard, while Mycelium Pharmacy is a single 503A compounder popular with med spas that you order from through its own portal. Fizy Health is an ordering platform like Refill that adds pass-through per-vial pricing before checkout and validation before you pay.

If you are weighing an ordering platform against ordering directly from Mycelium Pharmacy, this page lays out the platform-versus-pharmacy tradeoff and shows where a pass-through model like Fizy Health fits.

Compare Fizy Health vs Mycelium
Platform vs single compounder Multiple 503A partners Mycelium portal Pass-through pricing option Validation before payment Med spa and cash-pay clinics
Refill vs Mycelium

Refill vs Mycelium Pharmacy, capability by capability.

Refill is the ordering layer across several 503A pharmacies. Mycelium Pharmacy is one of the compounders that fills orders. The comparison is really platform versus pharmacy.

Platform model
Refill Telehealth infrastructure platform: pharmacy network, provider network, Refill Connect patient portal, and aggregate medication pricing.
Mycelium Pharmacy Single 503A compounding pharmacy serving med spas, ordered through its own provider portal.
Catalog scope
Refill 503A compounded medications across LegitScript-certified partner pharmacies; broader catalog scope may include additional supply channels.
Mycelium Pharmacy Mycelium's own compounded formulary, strong for med spa SKUs, limited to what Mycelium makes.
Pricing visibility
Refill Pre-negotiated aggregate medication pricing plus tiered software fees (roughly 1.5–5% on transactions per public tiers); confirm per-SKU landed cost at onboarding.
Mycelium Pharmacy Pricing set by Mycelium through your clinic account and its portal; rates vary by agreement.
Multi-pharmacy orders
Refill One dashboard routes orders to several 503A partners.
Mycelium Pharmacy Orders stay inside Mycelium's catalog and portal workflow.
Pre-submit validation
Refill Not highlighted in Refill public marketing or FAQ.
Mycelium Pharmacy Standard pharmacy review after submission inside Mycelium's portal.
Support
Refill Tiered standard support on platform plans; dedicated fulfillment coordination. No in-app ticketing advertised on refill.co.
Mycelium Pharmacy Mycelium pharmacy account and support channels.

  • When Refill fits

    You need multi-pharmacy routing plus outsourced 50-state prescribing or Refill Connect, and aggregate pricing beats your solo pharmacy contracts.

  • When Mycelium fits

    Mycelium is already your med spa 503A compounder, you order its SKUs, and its portal handles your daily workflow.

Mycelium Pharmacy details from its public website and portal materials (June 2026). Refill details from refill.co (June 2026).

Platform or pharmacy — which question are you really asking?

Comparing Refill to Mycelium Pharmacy compares two layers. Refill is software that routes orders to a network of compounders. Mycelium is one of those compounders, well suited to med spa formularies. A clinic can reach pharmacies like Mycelium through a platform, or order from Mycelium directly through its portal.

The decision is one pharmacy relationship or a dashboard across several. If you only order what Mycelium compounds, a single portal is simpler. If you batch across multiple compounders, an ordering platform removes the portal hopping — and the model you choose determines how pricing, validation, and support show up.

Where Fizy Health changes the comparison

Fizy Health is an ordering platform in the same category as Refill, but it shows resolved per-vial 503A cost on every catalog and cart line before checkout, with a disclosed facilitation fee at payment — so you quote cash-pay patients on real numbers without a sales call. Cart validation catches invalid SIGs, prescriber state mismatches, and stock gaps before you pay, not after a pharmacy rejects the order.

Refill, Mycelium, or a pass-through platform — which fits your clinic?

Refill fits if

Refill

You need outsourced prescribing, Refill Connect, or aggregate pharmacy leverage.

  • You need a 50-state provider network without hiring prescribers in every state.
  • Launch priority is Refill Connect — white-label patient portal, assessments, and billing.
  • Pre-negotiated aggregate pharmacy pricing beats your solo contracts and you accept tiered software fees.
Consider Fizy Health if

Fizy Health

Pass-through per-vial pricing and validation before you pay.

  • You want resolved per-vial 503A cost visible in catalog and cart before you quote cash-pay patients.
  • You want SIG and licensure issues caught before payment — not after a pharmacy rejects the order.
  • You batch refills across multiple 503A partners and want one cart, one validation pass, one checkout.
If you choose Fizy Health

What a pass-through ordering platform gives your clinic.

Whether you compare Refill to Mycelium or to Fizy Health, these are the outcomes when pricing is visible and orders are validated before you pay.

See all features
Keep comparing Refill

More Refill head-to-head comparisons.

See the full Refill guide
FAQ

Refill vs Mycelium Pharmacy questions.

  • Category

    Is Refill the same kind of thing as Mycelium Pharmacy?

    No. Refill is a telehealth infrastructure platform that routes clinic orders to multiple 503A compounding pharmacies, while Mycelium Pharmacy is a single 503A compounder. You can reach pharmacies like Mycelium through a platform, or order from Mycelium directly in its portal.

  • Pricing

    Does Refill or Mycelium show pricing up front?

    Neither publishes per-vial prices openly. Refill uses pre-negotiated aggregate pricing with tiered software fees; confirm per-SKU landed cost at onboarding, and Mycelium pricing is set through your clinic account. Fizy Health shows resolved per-vial 503A cost in catalog and cart before checkout.

  • Catalog

    Can I order more than Mycelium's medications through Refill?

    Yes. Because Refill aggregates several 503A partners, its catalog can span more than any single compounder. Ordering directly from Mycelium limits you to Mycelium's own compounded formulary.

  • Validation

    Does either catch order errors before submission?

    Refill public materials do not highlight pre-submit validation, and Mycelium applies standard pharmacy review after submission. Fizy Health runs cart validation before checkout to catch invalid SIGs, licensure mismatches, and stock gaps before you pay.

  • Support

    How does support differ between Refill and Mycelium?

    Refill offers tiered platform support and fulfillment coordination per refill.co, and Mycelium provides pharmacy account and support channels. Fizy Health offers in-app support tickets threaded to the order, patient, and clinic.

  • Alternative

    Where does Fizy Health fit between Refill and Mycelium?

    Fizy Health is an ordering platform like Refill that routes to LegitScript-certified 503A partners, but it adds pass-through per-vial pricing before checkout, pre-submit cart validation, and per-line tracking across compounders.

Sources reviewed June 2026

  • Mycelium Pharmacy public website and portal materials, reviewed June 2026.
  • Refill public website and FAQ (refill.co), reviewed June 2026.
  • Fizy Health platform capabilities reflect the live product.
Evaluate with real numbers

Compare pass-through pricing against both options.

See resolved per-vial 503A cost before you quote, with validation before you pay and one cart across partners. Free to start.

Fizy Health vs Mycelium Start Ordering Free