Refill vs OnlyScripts

Refill vs OnlyScripts

Refill and OnlyScripts both consolidate pharmacy ordering behind one login, but they emphasize different layers. Refill is telehealth infrastructure — pharmacy network, nationwide provider coverage, Refill Connect white-label patient tools, and pre-negotiated aggregate medication pricing plus tiered software fees. OnlyScripts is a single-login prescribing platform connecting providers to 20+ pharmacy partners with real-time price comparison across the network. Fizy Health is a pharmacy ops platform for clinics that already prescribe, with pass-through per-vial pricing before checkout and cart validation before you pay.

If you are choosing between Refill's telehealth stack and OnlyScripts' prescribing hub, this page compares the models and shows where a pass-through platform like Fizy Health fits.

Telehealth stack vs prescribing hub Provider network vs clinic prescribers Aggregate vs network comparison pricing Refill Connect vs price comparison Pass-through pricing option Cash-pay and telehealth clinics
Refill vs OnlyScripts

Refill vs OnlyScripts, capability by capability.

Both reduce portal sprawl. Refill bundles outsourced prescribing and patient-facing tools; OnlyScripts aggregates 20+ pharmacy partners behind one credential with real-time price comparison.

Platform model
Refill Telehealth infrastructure: LegitScript 503A pharmacy network, nationwide provider network, Refill Connect patient portal, and aggregate medication pricing.
OnlyScripts Single-login prescribing platform connecting providers to 20+ pharmacy partners with real-time price comparison.
50-state prescribing
Refill Nationwide provider network — hands-on (~$30) or hands-off (~$50) per encounter per public pricing.
OnlyScripts Clinic's own licensed prescribers; network focuses on pharmacy routing, not outsourced MD coverage.
White-label patient portal
Refill Refill Connect — branded assessments, patient portal, and billing (from ~$399/mo plus setup per public tiers).
OnlyScripts Prescriber-first dashboard; patient-facing UX varies by pharmacy partner in the network.
Pricing visibility
Refill Pre-negotiated aggregate 503A pricing plus tiered software fees (roughly 1.5–5% on transactions); catalog often confirmed at demo.
OnlyScripts Real-time price comparison across 20+ pharmacy partners in the OnlyScripts portal after onboarding.
Network breadth
Refill Multiple LegitScript 503A partners with aggregate leverage pricing.
OnlyScripts 20+ pharmacy partners spanning 503A, 503B, specialty, and retail per public marketing.
Pre-submit validation
Refill Platform ordering and fulfillment coordination; pre-submit hard-stop validation not publicly documented.
OnlyScripts Network and pharmacy review rather than advertised pre-submit cart validation.
  • When Refill fits

    You need outsourced 50-state prescribing, Refill Connect for a white-label patient launch, or aggregate pharmacy pricing with provider coverage — and you accept tiered software fees.

  • When OnlyScripts fits

    You want single-login access to browse and compare 20+ pharmacy networks in real time and need custom API integrations for enterprise telehealth.

OnlyScripts details from onlyscripts.co (June 2026). Refill details from refill.co and published pricing tiers (June 2026).

Telehealth stack or prescribing aggregation hub?

Refill and OnlyScripts both answer portal sprawl, but with different depth. Refill sells telehealth infrastructure — providers, Refill Connect, aggregate medication pricing, and software fees on transactions. OnlyScripts is a prescribing hub that puts 20+ pharmacy partners behind one login with real-time price comparison.

Pick by whether outsourced clinical coverage and a branded patient portal matter more than browsing the widest pharmacy network with comparison pricing. Either way, landed-cost clarity on the SKUs you actually order — not just network breadth — drives margin.

Where Fizy Health changes the comparison

Fizy Health is built for clinic ops teams who batch every patient order in one cart. It shows pass-through per-vial 503A cost before checkout — not aggregate pricing with software fees or pre-negotiated network comparison rates. Cart validation catches invalid SIGs, prescriber state mismatches, and stock gaps before you pay.

Refill, OnlyScripts, or a pass-through platform — which fits your clinic?

Refill fits if

Refill

You need outsourced prescribing, Refill Connect, or aggregate pharmacy leverage.

  • You need a 50-state provider network without hiring prescribers in every state.
  • Launch priority is Refill Connect — white-label patient portal, assessments, and billing.
  • Pre-negotiated aggregate pharmacy pricing beats your solo contracts and you accept tiered software fees.
Consider Fizy Health if

Fizy Health

Pass-through per-vial pricing and validation before you pay.

  • You employ licensed prescribers and need landed cost per vial before you quote cash-pay patients.
  • You want SIG and licensure issues caught before payment — not after a pharmacy rejects the order.
  • You batch refills across multiple 503A partners and want one cart, one validation pass, one checkout.
FAQ

Refill vs OnlyScripts questions.

  • Category

    Are Refill and OnlyScripts the same kind of platform?

    Both consolidate pharmacy ordering behind one login, but Refill is telehealth infrastructure with provider coverage, Refill Connect, and aggregate pricing plus software fees. OnlyScripts is a prescribing hub with real-time price comparison across 20+ pharmacy partners.

  • Network

    Which has the broader pharmacy network?

    OnlyScripts advertises 20+ pharmacy partners spanning 503A, 503B, specialty, and retail. Refill routes across multiple LegitScript 503A partners with aggregate leverage pricing. Breadth and landed cost on your formulary are different questions — compare your top SKUs on both.

  • Pricing

    How does Refill aggregate pricing compare to OnlyScripts comparison tool?

    Refill negotiates aggregate 503A pricing and charges tiered software fees on transactions. OnlyScripts shows real-time price comparison across network partners after onboarding. Fizy Health shows pass-through per-vial 503A cost before checkout.

  • Providers

    Does OnlyScripts include outsourced prescribing like Refill?

    Refill bundles a nationwide provider network with hands-on or hands-off encounters per public pricing. OnlyScripts focuses on pharmacy routing and price comparison for clinics that already prescribe.

  • Patient portal

    Which offers a white-label patient portal?

    Refill Connect provides branded assessments, patient portal, and billing on tiered monthly plans. OnlyScripts is prescriber-first. Fizy Health focuses on prescriber-side batch checkout rather than DTC patient portal infrastructure.

  • Alternative

    Where does Fizy Health fit between Refill and OnlyScripts?

    Fizy Health is a pharmacy ops platform for clinics that already prescribe. It adds pass-through per-vial pricing before checkout, pre-submit cart validation, and per-line batch checkout — without Refill's software fees or OnlyScripts' network comparison model.

Sources reviewed June 2026

  • OnlyScripts public website (onlyscripts.co), reviewed June 2026.
  • Refill public website and published pricing tiers (refill.co), reviewed June 2026.
  • Fizy Health platform capabilities reflect the live product.
Evaluate with real numbers

Compare pass-through pricing against both options.

See resolved per-vial 503A cost before you quote, with validation before you pay and one cart across partners. Free to start.