Fizy health
Refill pricing for clinics

What does Refill pricing mean for a clinic P&L?

For a clinic, Refill pricing is aggregate medication cost plus software economics: pre-negotiated 503A rates across Refill's network, tiered transaction fees published at roughly 1.5–5%, and platform subscriptions from free to about $299 per month. Because per-SKU rates are confirmed at demo rather than on a public catalog, you cannot model gross margin on semaglutide, tirzepatide, or hormones until onboarding — and you must add software fees and any monthly platform charge to get true cost of goods sold.

This page looks at Refill pricing through the clinic owner's P&L lens: what you can plan, what you cannot, and how visible per-vial cost changes margin math.

Compare Fizy Health vs Refill
Clinic P&L lens Aggregate medication rates Software fee on transactions Margin on GLP-1s Pass-through alternative Landed cost before consult

How Refill pricing shows up on a clinic P&L

On a cash-pay clinic P&L, compounded medications are cost of goods sold, and the spread between landed cost and patient price is gross margin. Refill's model sets COGS from aggregate pre-negotiated 503A rates plus a tiered software fee on each transaction, with optional monthly platform and Refill Connect charges. Until demo confirms your per-SKU medication rates and plan tier, you are estimating margin rather than confirming it. Software fees that scale with order volume can erode GLP-1 margin even when the aggregate drug rate looks competitive on paper.

What a clinic owner can and cannot plan up front

You can plan structure: which SKUs drive volume, refill cadence, and patient price points your market supports. What you cannot plan up front with Refill is the full COGS line, because medication rates are confirmed at demo and software fees depend on tier. That gap matters most for high-volume GLP-1 programs, where a small per-vial difference plus a percentage transaction fee multiplied across hundreds of monthly refills swings the bottom line. Before margin depends on it, ask for written per-vial cost on your top three SKUs, confirm your software fee percentage, and model total cost including platform subscription.

Also separate provider-network costs if you outsource encounters. Refill publishes hands-on encounters at about $30 and hands-off at about $50 per encounter. Those lines sit outside medication COGS but hit contribution margin on telehealth programs. Build your P&L on all-in landed cost per vial delivered plus any encounter and platform fees, not the headline aggregate medication rate alone.

When pass-through visibility changes clinic margin planning

Fizy Health is built for clinics that prescribe in-house and need margin visible before the consult. Resolved per-vial 503A cost appears on each catalog and cart line before checkout, with a disclosed facilitation fee at payment and no percentage software fee on transactions. That lets you model GLP-1 gross margin the same day you evaluate the platform, then batch a refill day in one cart with per-line cost you can export to a spreadsheet.

Run an honest parallel week: compare Refill's all-in cost at your tier against visible pass-through cost on the same semaglutide and tirzepatide strengths. If aggregate leverage plus fees wins on your top lines, Refill may fit. If pass-through visibility and batch checkout matter more for how your team runs refill day, Fizy Health is the better P&L tool.

Model margin on aggregate leverage — or on visible per-vial cost?

Refill fits if

Refill

Aggregate pricing plus bundled infrastructure justifies the fee stack.

  • Pre-negotiated aggregate rates beat your solo pharmacy contracts after software fees at your volume.
  • You need Refill Connect or outsourced prescribing and accept tiered transaction fees on top of medication cost.
  • You can confirm full P&L inputs at demo, including meet-or-beat terms on your top SKUs.
Consider Fizy Health if

Fizy Health

You prescribe in-house and need margin math before the consult.

  • You quote cash-pay GLP-1 patients and need per-vial 503A cost visible before you set program pricing.
  • You want drug cost and facilitation fee separate, without a percentage fee on every transaction.
  • You run high-volume refill days and need one cart with per-line landed cost before checkout.
If you choose Fizy Health

What your clinic P&L gets when cost is visible early.

Refill P&L inputs arrive at demo. These are the outcomes when per-vial cost is on screen before you order.

See all features
Keep evaluating Refill pricing

More on Refill economics for clinics.

See the full Refill pricing guide
FAQ

What clinic owners ask about Refill pricing.

  • P&L

    How does Refill pricing hit clinic gross margin?

    Refill COGS combines aggregate pre-negotiated 503A medication rates with tiered software fees on transactions, roughly 1.5–5% per published tiers, plus any monthly platform or Refill Connect subscription. Margin depends on all-in landed cost, not the medication rate alone.

  • Planning

    Can I model Refill margin before onboarding?

    Only partially. Platform tiers and software fee ranges are published, but per-SKU medication rates are confirmed at demo. You need written per-vial quotes on your top SKUs plus your tier's transaction fee to model GLP-1 margin accurately.

  • GLP-1

    Why do software fees matter more on GLP-1 volume?

    GLP-1 programs run high transaction counts. A percentage software fee on every order compounds across hundreds of monthly refills, so a competitive aggregate drug rate can still produce thinner margin than pass-through pricing with a disclosed flat facilitation fee.

  • Providers

    Do Refill provider encounter fees affect clinic P&L?

    Yes, if you use Refill's outsourced provider network. Hands-on encounters are published at about $30 and hands-off at about $50 per encounter. Those costs sit outside medication COGS but reduce contribution margin on telehealth programs.

  • Comparison

    How does Fizy Health change clinic margin planning?

    Fizy Health shows resolved per-vial 503A cost before checkout with a disclosed facilitation fee and no percentage transaction fee, so clinic owners can model margin on GLP-1 and hormone SKUs the same day they evaluate the platform.

  • Verification

    What should I get in writing before signing with Refill?

    Per-vial cost on your top three SKUs, your software fee percentage and platform tier, meet-or-beat guarantee terms, and any separate charges for shipping, Connect, setup, or provider encounters so your P&L reflects true landed cost.

Sources reviewed June 2026

  • Refill public website and published pricing tiers in Refill web app (refill.co), reviewed June 2026.
  • Fizy Health platform capabilities reflect the live product.
Evaluate with real numbers

Model margin on numbers you can see today.

Compare landed per-vial cost on your top GLP-1 and hormone SKUs, batch one refill day, and decide with real P&L math. Free to start.

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