How to compare month and multi-month on Refill
Ask Refill for written per-vial cost on both monthly and multi-month options at the same strength. Divide each by doses supplied to get per-dose drug cost. Add software fee percentage on the full transaction value. Add shipping allocated per dose. Compare normalized per-dose landed cost, not the bigger vial's headline price.
For GLP-1 programs, ask whether multi-month vials fit your titration protocol. Patients who titrate up mid-vial may waste supply or need early reorders that reset economics. For TRT and stable-dose hormones, multi-month supply often wins on per-dose cost if rates stay stable across refill cycles. Confirm rate stability in writing, not just the first multi-month quote.